Australian Placental Transfusion Study (APTS)
A large trial that compared waiting at least 60 seconds with clamping the cord within 10 seconds in babies expected to be born before 30 weeks.
- Study
- In this atlas
Overview
- Design
- Randomised trial in which fetuses of women expected to deliver before 30 weeks of gestation were assigned to immediate cord clamping (10 seconds or less after delivery) or delayed clamping (60 seconds or more after delivery). Intention-to-treat analysis accounting for multiple births.
- Phase
- Not reported
- Enrolled
- 1,634 fetuses (women expected to deliver before 30 weeks)
- Sponsor
- Not recorded
- Funder
- Not recorded
- Registry
-
ACTRN12610000633088
-
- Started
- Not reported
- Primary completion
- Not reported
- Completion
- Not reported
- Countries
- Australia, New Zealand, United Kingdom, Pakistan, France, United States, Canada
- Care setting
- Not reported
- Registry status
- Not reported
Technical summary
Multicentre randomised trial reported in 2017. The registry number printed in the abstract is ACTRN12610000633088 (ANZCTR); the registry record was not fetched. 1634 fetuses were randomised and 1566 were born alive before 30 weeks (782 immediate clamping, 784 delayed clamping). Primary composite outcome: death or major morbidity by 36 weeks of postmenstrual age. The abstract names the Australian National Health and Medical Research Council and the NHMRC Clinical Trials Centre as funders.
Arms
-
Immediate cord clamping
Intervention Delayed umbilical cord clamping
Cord clamped 10 seconds or less after delivery. The median time to clamping was 5 seconds.
-
Delayed cord clamping
Intervention Delayed umbilical cord clamping
Cord clamped 60 seconds or more after delivery. The median time to clamping was 60 seconds.
Findings
No findings are published for this study.
Record details
- Record id
maternal:apts-trial- Content hash
4cb6ddd6fb38c1aa995c19046efe44cf529ea89ed18b34864f80f3b2af73c52e