# Australian Placental Transfusion Study (APTS)

Study · id `maternal:apts-trial` · Maternal & Newborn Atlas · release `c7fb95f1d15a7d13` (public)

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Browse, life stage: Childbirth; Newborn  
Browse, care area: Preterm and sick newborns  

## In plain language

A large trial that compared waiting at least 60 seconds with clamping the cord within 10 seconds in babies expected to be born before 30 weeks.

## Technical summary

Multicentre randomised trial reported in 2017. The registry number printed in the abstract is ACTRN12610000633088 (ANZCTR); the registry record was not fetched. 1634 fetuses were randomised and 1566 were born alive before 30 weeks (782 immediate clamping, 784 delayed clamping). Primary composite outcome: death or major morbidity by 36 weeks of postmenstrual age. The abstract names the Australian National Health and Medical Research Council and the NHMRC Clinical Trials Centre as funders.

## Key facts

- Design: Randomised trial in which fetuses of women expected to deliver before 30 weeks of gestation were assigned to immediate cord clamping (10 seconds or less after delivery) or delayed clamping (60 seconds or more after delivery). Intention-to-treat analysis accounting for multiple births.
- Phase: Not reported
- Enrolled: 1634 fetuses (women expected to deliver before 30 weeks) (randomized count; Delayed versus Immediate Cord Clamping in Preterm Infants, snapshot `maternal:pubmed-29081267-2026-10-14`, retrieved 2026-10-14)
- Started: Not reported
- Primary completion: Not reported
- Completion: Not reported
- Countries: Australia; New Zealand; United Kingdom; Pakistan; France; United States; Canada (Australian Placental Transfusion Study (ANZCTR record), snapshot `maternal:apts-anzctr-2026-10-14`, retrieved 2026-10-14)
- Care setting: Not reported
- Registry status: Not reported

## Connected pages

- Compares delayed with immediate clamping: Delayed umbilical cord clamping (`maternal:delayed-cord-clamping`)

## Provenance

Content hash: 4cb6ddd6fb38c1aa995c19046efe44cf529ea89ed18b34864f80f3b2af73c52e
Last substantive edit: 2026-10-14
Evidence last checked: Not recorded