Blood pressure self-monitoring and physician-guided dose changes after birth
Measuring your own blood pressure at home after birth and following an app that suggests changes to blood pressure medicine, with doctors checking the readings and approving the changes. It was tested in one UK trial of women who had had pre-eclampsia or gestational hypertension, and their blood pressure was lower about 9 months after birth than with usual care.
- Intervention
- In this atlas
Overview
Technical summary
The strategy tested in POP-HT: a Bluetooth home blood pressure monitor and a smartphone app with a medicine-titration algorithm, with physicians who can review uploaded readings and respond to abnormal readings (registry description). The trial found lower 24-hour blood pressure at about 249 days after birth (diastolic -5.80 mm Hg, systolic -6.51 mm Hg). It is one single-site trial, and its outcome is blood pressure, not heart or blood vessel events. No guideline recommendation on this strategy was read. It links to the core record for home blood pressure monitoring.
About this intervention
- Type
- Service
- Mechanism
- The woman measures her own blood pressure with a Bluetooth home monitor and follows a smartphone app that gives advice on changing her medicine dose; physicians review the uploaded readings and approve any change (registry description).
Claims and evidence
Context Women after a pregnancy with pre-eclampsia or gestational hypertension who needed blood pressure medicine at discharge, POP-HT trial, UK
- Recipient
- Maternal
- Population
- Women aged 18 years or older whose pregnancy was complicated by pre-eclampsia or gestational hypertension and who needed blood pressure medicine after birth when they were discharged (abstract eligibility). In the trial, 40% had gestational hypertension and 60% had pre-eclampsia, and the mean age was 32.6 years. The outcome is the woman's own blood pressure, so the recipient and the measured population are the same. The registry excludes women with pre-existing hypertension.
- Care setting
- A single hospital in the UK (abstract). The registry lists two sites, both in Oxford.
- Geography
- United Kingdom
- Life stage
- Postnatal period: the primary outcome was measured about 249 days after birth, in the first 9 months postpartum
- Gestational age
- Not reported
- Postnatal age
- Not reported
- Follow-up
- About 9 months after birth (abstract). The 24-hour blood pressure was measured at about 249 days postpartum. The registry gives the primary outcome time frame as 6 months postpartum.
Eligibility: 3 inclusion criteria; 1 exclusion criterion
- Included
- Aged 18 years or older
- Pregnancy complicated by pre-eclampsia or gestational hypertension
- Needed blood pressure medicine after birth when discharged
- Excluded
- Women with pre-existing hypertension (registry exclusion criteria); the registry lists other exclusions that are not repeated here
In POP-HT, a randomised trial at a single UK hospital, 220 women who had had pre-eclampsia or gestational hypertension and still needed blood pressure medicine at discharge were assigned to self-monitoring with doctor-guided changes in their medicine (112 women) or to usual postnatal care (108 women). Of them, 200 (91%) were in the primary analysis. At about 249 days after birth, 24-hour mean diastolic blood pressure was 71.2 mm Hg with the intervention and 76.6 mm Hg with usual care, a between-group difference of -5.80 mm Hg (95% CI -7.40 to -4.20; P < .001). Systolic pressure was 114.0 and 120.3 mm Hg, a difference of -6.51 mm Hg (95% CI -8.80 to -4.22; P < .001).
Applies to Maternal- Women aged 18 years or older whose pregnancy was complicated by pre-eclampsia or gestational hypertension and who needed blood pressure medicine after birth when they were discharged (abstract eligibility). In the trial, 40% had gestational hypertension and 60% had pre-eclampsia, and the mean age was 32.6 years. The outcome is the woman's own blood pressure, so the recipient and the measured population are the same. The registry excludes women with pre-existing hypertension.
- A single hospital in the UK (abstract). The registry lists two sites, both in Oxford.
- United Kingdom
- Postnatal period: the primary outcome was measured about 249 days after birth, in the first 9 months postpartum
- Gestational age Not reported
- Postnatal age Not reported
- Certainty method
- Not assessed
- Limitations
- The trial was open-label with a blinded end point, run at one site, and the authors call the result an association in a single-centre trial. The outcome is blood pressure, not a heart or blood vessel event; the abstract reports no such events. The registry record was last updated on 2021-10-22 and still lists an estimated enrolment of 200, an estimated primary completion date of 2022-04-01 and a primary outcome time frame of 6 months, against 220 randomised and 9 months in the paper. The two records are kept side by side and are not reconciled. Only the PubMed abstract was read; the PMC copy is not in the open access subset.
- Last checked
- 2026-10-15
- Next evidence check due
- Not scheduled
Sources and citations (13)
-
- Locator
- Abstract, RESULTS, sentence 1
- How it applies
- PubMed abstract of the JAMA 2023 trial report.
- Retrieved
- Source effective date
- Not reported
- Source state
- Current
- Snapshot hash
6d59f07afba300ca863482def34fb95d2e38a506d4185033a15ae18e6c91f28b- Reuse basis
- PubMed record fetched through NCBI E-utilities. Only the hash of the bytes is kept, because publisher copyright may apply to the abstract (https://pubmed.ncbi.nlm.nih.gov/disclaimer/). Short factual quotations under 25 words, with the citation.
-
- Locator
- Abstract, RESULTS, sentence 3
- How it applies
- PubMed abstract.
- Retrieved
- Source effective date
- Not reported
- Source state
- Current
- Snapshot hash
6d59f07afba300ca863482def34fb95d2e38a506d4185033a15ae18e6c91f28b- Reuse basis
- PubMed record fetched through NCBI E-utilities. Only the hash of the bytes is kept, because publisher copyright may apply to the abstract (https://pubmed.ncbi.nlm.nih.gov/disclaimer/). Short factual quotations under 25 words, with the citation.
-
- Locator
- Abstract, RESULTS, sentence 4, fragment 1 of 2
- How it applies
- PubMed abstract.
- Retrieved
- Source effective date
- Not reported
- Source state
- Current
- Snapshot hash
6d59f07afba300ca863482def34fb95d2e38a506d4185033a15ae18e6c91f28b- Reuse basis
- PubMed record fetched through NCBI E-utilities. Only the hash of the bytes is kept, because publisher copyright may apply to the abstract (https://pubmed.ncbi.nlm.nih.gov/disclaimer/). Short factual quotations under 25 words, with the citation.
-
- Locator
- Abstract, RESULTS, sentence 5
- How it applies
- PubMed abstract.
- Retrieved
- Source effective date
- Not reported
- Source state
- Current
- Snapshot hash
6d59f07afba300ca863482def34fb95d2e38a506d4185033a15ae18e6c91f28b- Reuse basis
- PubMed record fetched through NCBI E-utilities. Only the hash of the bytes is kept, because publisher copyright may apply to the abstract (https://pubmed.ncbi.nlm.nih.gov/disclaimer/). Short factual quotations under 25 words, with the citation.
-
- Locator
- Abstract, RESULTS, sentence 6, fragment 1 of 2
- How it applies
- PubMed abstract.
- Retrieved
- Source effective date
- Not reported
- Source state
- Current
- Snapshot hash
6d59f07afba300ca863482def34fb95d2e38a506d4185033a15ae18e6c91f28b- Reuse basis
- PubMed record fetched through NCBI E-utilities. Only the hash of the bytes is kept, because publisher copyright may apply to the abstract (https://pubmed.ncbi.nlm.nih.gov/disclaimer/). Short factual quotations under 25 words, with the citation.
-
- Locator
- Abstract, RESULTS, sentence 7
- How it applies
- PubMed abstract.
- Retrieved
- Source effective date
- Not reported
- Source state
- Current
- Snapshot hash
6d59f07afba300ca863482def34fb95d2e38a506d4185033a15ae18e6c91f28b- Reuse basis
- PubMed record fetched through NCBI E-utilities. Only the hash of the bytes is kept, because publisher copyright may apply to the abstract (https://pubmed.ncbi.nlm.nih.gov/disclaimer/). Short factual quotations under 25 words, with the citation.
-
- Locator
- Abstract, INTERVENTIONS, sentence 1
- How it applies
- What the two groups received.
- Retrieved
- Source effective date
- Not reported
- Source state
- Current
- Snapshot hash
6d59f07afba300ca863482def34fb95d2e38a506d4185033a15ae18e6c91f28b- Reuse basis
- PubMed record fetched through NCBI E-utilities. Only the hash of the bytes is kept, because publisher copyright may apply to the abstract (https://pubmed.ncbi.nlm.nih.gov/disclaimer/). Short factual quotations under 25 words, with the citation.
-
- Locator
- Abstract, DESIGN, SETTING, AND PARTICIPANTS, sentence 2
- How it applies
- Who could take part.
- Retrieved
- Source effective date
- Not reported
- Source state
- Current
- Snapshot hash
6d59f07afba300ca863482def34fb95d2e38a506d4185033a15ae18e6c91f28b- Reuse basis
- PubMed record fetched through NCBI E-utilities. Only the hash of the bytes is kept, because publisher copyright may apply to the abstract (https://pubmed.ncbi.nlm.nih.gov/disclaimer/). Short factual quotations under 25 words, with the citation.
-
- Locator
- Abstract, MAIN OUTCOMES AND MEASURES, sentence 1
- How it applies
- The primary outcome.
- Retrieved
- Source effective date
- Not reported
- Source state
- Current
- Snapshot hash
6d59f07afba300ca863482def34fb95d2e38a506d4185033a15ae18e6c91f28b- Reuse basis
- PubMed record fetched through NCBI E-utilities. Only the hash of the bytes is kept, because publisher copyright may apply to the abstract (https://pubmed.ncbi.nlm.nih.gov/disclaimer/). Short factual quotations under 25 words, with the citation.
-
Background Physician Optimised Post-partum Hypertension Treatment Trial
- Locator
- protocolSection.outcomesModule.primaryOutcomes[0].timeFrame
- How it applies
- The registry gives 6 months postpartum for the primary outcome.
- Retrieved
- Source effective date
- 2021-10-22
- Source state
- Current
- Snapshot hash
18fb97faaf4bb6fea5b57809e872bfddbbffe6d62fa9556698a5439f31f5cc59- Reuse basis
- Registry record. The raw API JSON is committed at research/snapshots/mk-ctgov-NCT04273854.json. The ClinicalTrials.gov terms page is rendered by JavaScript and its text was not read by a script, so the redistribution basis is unverified; any quotation stays short.
-
- Locator
- Abstract, RESULTS, sentence 4, fragment 2 of 2
- How it applies
- PubMed abstract.
- Retrieved
- Source effective date
- Not reported
- Source state
- Current
- Snapshot hash
6d59f07afba300ca863482def34fb95d2e38a506d4185033a15ae18e6c91f28b- Reuse basis
- PubMed record fetched through NCBI E-utilities. Only the hash of the bytes is kept, because publisher copyright may apply to the abstract (https://pubmed.ncbi.nlm.nih.gov/disclaimer/). Short factual quotations under 25 words, with the citation.
-
- Locator
- Abstract, RESULTS, sentence 6, fragment 2 of 2
- How it applies
- PubMed abstract.
- Retrieved
- Source effective date
- Not reported
- Source state
- Current
- Snapshot hash
6d59f07afba300ca863482def34fb95d2e38a506d4185033a15ae18e6c91f28b- Reuse basis
- PubMed record fetched through NCBI E-utilities. Only the hash of the bytes is kept, because publisher copyright may apply to the abstract (https://pubmed.ncbi.nlm.nih.gov/disclaimer/). Short factual quotations under 25 words, with the citation.
-
- Locator
- Abstract, RESULTS, sentence 2
- How it applies
- PubMed abstract.
- Retrieved
- Source effective date
- Not reported
- Source state
- Current
- Snapshot hash
6d59f07afba300ca863482def34fb95d2e38a506d4185033a15ae18e6c91f28b- Reuse basis
- PubMed record fetched through NCBI E-utilities. Only the hash of the bytes is kept, because publisher copyright may apply to the abstract (https://pubmed.ncbi.nlm.nih.gov/disclaimer/). Short factual quotations under 25 words, with the citation.
Clinical links
Each link reports what one cited claim says about one population. "Evaluated for" means studied, not shown to work. These links do not show that anything is effective or right for you.
-
Claim, not a settled fact POP-HT: lower 24-hour blood pressure about 9 months after birth in women after pre-eclampsia or gestational hypertension (one single-site trial): High blood pressure after birth (mother)
Applies to Maternal- Women aged 18 years or older whose pregnancy was complicated by pre-eclampsia or gestational hypertension and who needed blood pressure medicine after birth when they were discharged (abstract eligibility). In the trial, 40% had gestational hypertension and 60% had pre-eclampsia, and the mean age was 32.6 years. The outcome is the woman's own blood pressure, so the recipient and the measured population are the same. The registry excludes women with pre-existing hypertension.
- A single hospital in the UK (abstract). The registry lists two sites, both in Oxford.
- United Kingdom
- Postnatal period: the primary outcome was measured about 249 days after birth, in the first 9 months postpartum
- Gestational age Not reported
- Postnatal age Not reported
In POP-HT, a randomised trial at a single UK hospital, 220 women who had had pre-eclampsia or gestational hypertension and still needed blood pressure medicine at discharge were assigned to self-monitoring with doctor-guided changes in their medicine (112 women) or to usual postnatal care (108 women). Of them, 200 (91%) were in the primary analysis. At about 249 days after birth, 24-hour mean diastolic blood pressure was 71.2 mm Hg with the intervention and 76.6 mm Hg with usual care, a between-group difference of -5.80 mm Hg (95% CI -7.40 to -4.20; P < .001). Systolic pressure was 114.0 and 120.3 mm Hg, a difference of -6.51 mm Hg (95% CI -8.80 to -4.22; P < .001).Limitations. The trial was open-label with a blinded end point, run at one site, and the authors call the result an association in a single-centre trial. The outcome is blood pressure, not a heart or blood vessel event; the abstract reports no such events. The registry record was last updated on 2021-10-22 and still lists an estimated enrolment of 200, an estimated primary completion date of 2022-04-01 and a primary outcome time frame of 6 months, against 220 randomised and 9 months in the paper. The two records are kept side by side and are not reconciled. Only the PubMed abstract was read; the PMC copy is not in the open access subset.
Record details
- Record id
maternal:postpartum-bp-self-management- Content hash
47e177e9ac5d5afcf6c78d10829da438f1a2b5652f5288b334e5a459ba66955c