Tranexamic acid

Tranexamic acid is a medicine that reduces bleeding by blocking the breakdown of blood clots. This atlas meets it in two separate roles, kept on separate pages: to treat heavy bleeding after birth that has started, and to try to prevent bleeding after birth. The two uses have different evidence.

  • Drug
  • In this atlas

Overview

Technical summary

Drug, level substance. RxCUI 10691 (RxNav name tranexamic acid, term type IN) read 2026-10-14. Mechanism (WOMAN introduction): it inhibits the enzymatic breakdown of fibrinogen and fibrin by plasmin. Uses kept apart: treatment of postpartum haemorrhage (the WOMAN trial and 2025 global Recommendation 27, on the existing treatment record) and prevention (WOMAN-2 and 2025 global Recommendations 14 and 15, on the prevention record). WOMAN-2 and the NCT03475342 registry record name the drug as the trial intervention. No clinical claim sits on this page.

About this drug

Level
Substance
Mechanism
Inhibits the enzymatic breakdown of fibrinogen and fibrin by plasmin (WOMAN introduction).

Claims and evidence

No claims are published for this drug yet.

Record details

Record id
maternal:tranexamic-acid
Content hash
ca917e3acdb0f72b21d66f5628ed02886b64dfbcc8cf5f571fe186574d0c1106