Pregnancy

High blood pressure that a woman already has when she becomes pregnant, or that is found in the first 20 weeks. It is a form of high blood pressure, but decisions in pregnancy differ: some blood...

Condition 0 claims Evidence checked not recorded

High blood pressure that is present before pregnancy or starts during it. NICE groups these disorders in three ways: high blood pressure that was there before pregnancy or appeared in the first 20...

Condition 1 claim Evidence checked not recorded

A condition of pregnancy in which blood pressure rises after 20 weeks and, at the same time, there are signs that other parts of the body are affected. These can include protein in the urine, or...

Condition 0 claims Evidence checked not recorded

Birth before 37 completed weeks of pregnancy. The term covers two things: the baby who is born early, and the pregnancy that is likely to end early. WHO writes its advice on steroid injections before...

Condition 0 claims Evidence checked not recorded

Steroid medicines, dexamethasone or betamethasone, given by injection to a pregnant woman who is likely to give birth early. The medicine reaches the baby and helps the lungs mature, which can...

Intervention 7 claims Evidence checked not recorded

Using blood pressure medicines in pregnancy when blood pressure is raised but not yet severe, instead of waiting until it becomes severe. This is a treatment strategy, not one drug. Different sources...

Intervention 5 claims Evidence checked not recorded

A small daily dose of aspirin taken during pregnancy by women at higher risk of pre-eclampsia, to help prevent it. In England, NICE tells clinicians to advise 75 mg to 150 mg a day, from 12 weeks of...

Intervention 2 claims Evidence checked 2026-10-12

A blood test for placental growth factor (PlGF), alone or as a ratio with a second protein, used together with a clinician's usual assessment when pre-eclampsia is suspected before 37 weeks...

Intervention 1 claim Evidence checked 2026-10-12

A pair of blood tests from Roche Diagnostics, run in a laboratory, whose results are combined into the sFlt-1/PlGF ratio. In the United States the FDA cleared it in February 2025 as an aid in judging...

Product 2 claims Evidence checked 2026-10-12

Two blood tests run on the same sample in a laboratory machine, one for sFlt-1 and one for placental growth factor (PlGF), with the result reported as the ratio of the two. Different companies build...

Technology 1 claim Evidence checked 2026-10-12

A blood test result for a pregnant woman: two proteins, sFlt-1 and placental growth factor (PlGF), are measured in the same sample, and the first is divided by the second. The test is used in two...

Biomarker 2 claims Evidence checked 2026-10-12

NICE uses the term nulliparity without defining it. MeSH files it under parity, which MeSH defines as "The number of offspring a female has borne." NICE lists it as one of six moderate risk factors...

Risk factor 1 claim Evidence checked 2026-10-12

The main report of the CHAP trial, published in 2022, on treating mild chronic hypertension during pregnancy.

Publication Evidence checked not recorded

The NICE guideline on diagnosing and managing high blood pressure in pregnancy, first published in June 2019 and last updated in April 2023.

Publication Evidence checked not recorded

A large trial in the United States that asked whether women with mildly raised blood pressure before or early in pregnancy do better if they take blood pressure medicine to keep their pressure under...

Study Evidence checked not recorded

A trial in 29 hospitals in Bangladesh, India, Kenya, Nigeria and Pakistan. Pregnant women who were likely to give birth early received either a dexamethasone steroid injection or a dummy injection...

Study 1 claim Evidence checked not recorded

A suggested order for reading this atlas, from before pregnancy through birth to a baby’s first months. Each step points to one page and says in plain words what that page covers. It is a reading...

Reading path Evidence checked not recorded