{
  "release_id": "c7fb95f1d15a7d13",
  "id": "maternal:postpartum-depression",
  "owner": "maternal",
  "kind": "condition",
  "slug": "postpartum-depression",
  "name": "Postpartum depression (mother)",
  "aliases": [],
  "atlases": [
    "maternal"
  ],
  "summary_plain": "Depression after childbirth. Many new mothers have short spells of low mood, tearfulness or worry known as the baby blues, which usually pass within a few days to a week. Postpartum depression is more intense and lasts longer than two weeks, and it can begin anytime in the first year after the birth. It is common, serious and treatable.",
  "summary_technical": "MedlinePlus (from the Office on Women's Health) describes postpartum depression as a common but serious mood disorder that can begin anytime within the first year after childbirth, separate from the baby blues that go away within a few days to a week. NIMH treats it as the part of perinatal depression that follows birth. MedlinePlus lists talk therapy and medicines, including antidepressants, as treatments. US regulators have approved two medicines whose labelled use is postpartum depression: Zulresso (brexanolone) injection, given as a 60-hour infusion, labelled for adults in 2019 and for patients 15 years and older since a 2022 supplement, and now listed as discontinued; and Zurzuvae (zuranolone) capsules taken by mouth for 14 days, labelled for adults. The recipient is the postpartum woman.",
  "editorial_state": "draft",
  "last_substantive_edit": "2026-10-14",
  "last_evidence_check": "2026-10-14",
  "next_review_due": null,
  "identifiers": [],
  "navigation": {
    "maternal": {
      "life-stage": [
        "postpartum"
      ],
      "care-area": [
        "maternal-mental-health"
      ]
    }
  },
  "payload": {
    "recognition": "MedlinePlus lists feeling sad or empty most of the time, changes in eating and sleeping, crying more than usual, pulling away from family and friends, feeling little or no interest in the baby, constant doubts about caring for the baby, and thinking of harming oneself or the baby. Symptoms are more intense and last longer than the baby blues.",
    "assessment": "MedlinePlus says a provider may use screening questions or questionnaires and a clinical evaluation based on symptoms, with blood tests if needed to check for physical conditions such as thyroid disorders.",
    "burden_claims": []
  },
  "content_digest": "30b1182943fa5e4a3667b8abea77e60f6055df9ea8d7ac64912c78002eef9c89",
  "review": {
    "content_digest": "30b1182943fa5e4a3667b8abea77e60f6055df9ea8d7ac64912c78002eef9c89",
    "current": [],
    "conflicting": [],
    "stale": [],
    "inactive": []
  },
  "claims": [],
  "decisions": [],
  "milestones": [],
  "relationships": {
    "outgoing": [
      {
        "predicate": "subtype_of",
        "label": "Depression that begins after the birth",
        "clinical_claim_not_fact": false,
        "family": "navigation",
        "other_entity_id": "maternal:perinatal-depression",
        "other_entity_in_atlas": true,
        "claim_id": null,
        "evidence": null,
        "primary": true,
        "role": null,
        "valid_from": null,
        "valid_to": null
      },
      {
        "predicate": "related_to",
        "label": "MedlinePlus health information on this subject",
        "clinical_claim_not_fact": false,
        "family": "navigation",
        "other_entity_id": "core:medlineplus",
        "other_entity_in_atlas": true,
        "claim_id": null,
        "evidence": null,
        "primary": false,
        "role": null,
        "valid_from": null,
        "valid_to": null
      },
      {
        "predicate": "part_of",
        "label": "Filed under this front",
        "clinical_claim_not_fact": false,
        "family": "navigation",
        "other_entity_id": "maternal:front-mental-health-and-support",
        "other_entity_in_atlas": true,
        "claim_id": null,
        "evidence": null,
        "primary": true,
        "role": null,
        "valid_from": null,
        "valid_to": null
      }
    ],
    "incoming": [
      {
        "predicate": "related_to",
        "label": "Related to",
        "clinical_claim_not_fact": false,
        "family": "navigation",
        "other_entity_id": "maternal:postnatal-care",
        "other_entity_in_atlas": true,
        "claim_id": null,
        "evidence": null,
        "primary": false,
        "role": null,
        "valid_from": null,
        "valid_to": null
      },
      {
        "predicate": "treats",
        "label": "Treated by",
        "clinical_claim_not_fact": true,
        "family": "clinical",
        "other_entity_id": "maternal:brexanolone",
        "other_entity_in_atlas": true,
        "claim_id": "maternal:claim-brexanolone-trials-hamd-60-hours",
        "evidence": null,
        "primary": false,
        "role": null,
        "valid_from": null,
        "valid_to": null
      },
      {
        "predicate": "treats",
        "label": "Treated by",
        "clinical_claim_not_fact": true,
        "family": "clinical",
        "other_entity_id": "maternal:zuranolone",
        "other_entity_in_atlas": true,
        "claim_id": "maternal:claim-zuranolone-skylark-hamd-day-15",
        "evidence": null,
        "primary": false,
        "role": null,
        "valid_from": null,
        "valid_to": null
      },
      {
        "predicate": "treats",
        "label": "Treated by",
        "clinical_claim_not_fact": true,
        "family": "clinical",
        "other_entity_id": "maternal:zulresso",
        "other_entity_in_atlas": true,
        "claim_id": "maternal:claim-zulresso-ppd-efficacy",
        "evidence": null,
        "primary": false,
        "role": null,
        "valid_from": null,
        "valid_to": null
      },
      {
        "predicate": "treats",
        "label": "Treated by",
        "clinical_claim_not_fact": true,
        "family": "clinical",
        "other_entity_id": "maternal:zurzuvae",
        "other_entity_in_atlas": true,
        "claim_id": "maternal:claim-zurzuvae-ppd-efficacy",
        "evidence": null,
        "primary": false,
        "role": null,
        "valid_from": null,
        "valid_to": null
      }
    ]
  },
  "page_path": "conditions/postpartum-depression/",
  "context_path": "api/v1/context/maternal--postpartum-depression.md"
}