{
  "release_id": "fc5a600ec7387e71",
  "id": "maternal:magnesium-sulfate",
  "owner": "maternal",
  "kind": "drug",
  "slug": "magnesium-sulfate",
  "name": "Magnesium sulfate",
  "aliases": [],
  "atlases": [
    "maternal"
  ],
  "summary_plain": "Magnesium sulfate is a mineral salt that is given by injection or drip as a medicine. This atlas meets it in two separate roles, kept on separate pages: to prevent and treat seizures in eclampsia, and to protect the baby's brain before a very early preterm birth. What research shows for one role does not carry over to the other.",
  "summary_technical": "Drug, level substance. RxCUI 6585 (RxNav name magnesium sulfate, term type IN) read 2026-10-14. Uses kept apart: eclampsia (the Magpie trial and the Collaborative Eclampsia Trial, on the eclampsia page) and fetal neuroprotection before preterm birth (on its own page). The BEAM trial (2008, PMID 18753646) tested the second use; this page only points to it. The abstracts spell the substance magnesium sulphate or sulfate. No clinical claim sits on this page.",
  "editorial_state": "draft",
  "last_substantive_edit": "2026-10-15",
  "last_evidence_check": "2026-10-14",
  "next_review_due": null,
  "identifiers": [
    {
      "scheme": "rxnorm",
      "value": "6585",
      "normalized_value": "6585",
      "match": "exact",
      "version": null,
      "label": null,
      "from_source": false
    }
  ],
  "navigation": {
    "maternal": {
      "life-stage": [
        "pregnancy",
        "childbirth"
      ],
      "care-area": [
        "pregnancy-conditions"
      ]
    }
  },
  "payload": {
    "level": "substance",
    "mechanism": null
  },
  "content_digest": "690effe0dc0cf624261946cf970527fd75f6ff37b081c89dfb5ee00dd985a406",
  "review": {
    "content_digest": "690effe0dc0cf624261946cf970527fd75f6ff37b081c89dfb5ee00dd985a406",
    "current": [],
    "conflicting": [],
    "stale": [],
    "inactive": []
  },
  "claims": [],
  "decisions": [],
  "milestones": [],
  "relationships": {
    "outgoing": [
      {
        "predicate": "related_to",
        "label": "Substance used in the eclampsia strategy",
        "clinical_claim_not_fact": false,
        "family": "navigation",
        "other_entity_id": "maternal:magnesium-sulfate-eclampsia",
        "other_entity_in_atlas": true,
        "claim_id": null,
        "evidence": null,
        "primary": false,
        "role": null,
        "valid_from": null,
        "valid_to": null
      },
      {
        "predicate": "part_of",
        "label": "Filed under this front",
        "clinical_claim_not_fact": false,
        "family": "navigation",
        "other_entity_id": "maternal:front-medicines-and-vaccines",
        "other_entity_in_atlas": true,
        "claim_id": null,
        "evidence": null,
        "primary": true,
        "role": null,
        "valid_from": null,
        "valid_to": null
      }
    ],
    "incoming": [
      {
        "predicate": "related_to",
        "label": "Related to",
        "clinical_claim_not_fact": false,
        "family": "navigation",
        "other_entity_id": "maternal:magnesium-sulfate-fetal-neuroprotection",
        "other_entity_in_atlas": true,
        "claim_id": null,
        "evidence": null,
        "primary": false,
        "role": null,
        "valid_from": null,
        "valid_to": null
      },
      {
        "predicate": "investigates",
        "label": "Investigated in",
        "clinical_claim_not_fact": false,
        "family": "sourced",
        "other_entity_id": "maternal:beam-trial",
        "other_entity_in_atlas": true,
        "claim_id": null,
        "evidence": {
          "snapshot_id": "maternal:ctgov-nct00014989-2026-10-15",
          "locator": "protocolSection.armsInterventionsModule.interventions[0].name"
        },
        "primary": false,
        "role": null,
        "valid_from": null,
        "valid_to": null
      },
      {
        "predicate": "investigates",
        "label": "Investigated in",
        "clinical_claim_not_fact": false,
        "family": "sourced",
        "other_entity_id": "maternal:magpie-trial",
        "other_entity_in_atlas": true,
        "claim_id": null,
        "evidence": {
          "snapshot_id": "maternal:pubmed-12057549-2026-10-14",
          "locator": "Abstract, METHODS, sentence 2"
        },
        "primary": false,
        "role": null,
        "valid_from": null,
        "valid_to": null
      }
    ]
  },
  "page_path": "drugs/magnesium-sulfate/",
  "context_path": "api/v1/context/maternal--magnesium-sulfate.md"
}