{
  "release_id": "15708f235d73cd42",
  "id": "maternal:hypertensive-disorders-of-pregnancy",
  "owner": "maternal",
  "kind": "condition",
  "slug": "hypertensive-disorders-of-pregnancy",
  "name": "Hypertensive disorders of pregnancy",
  "aliases": [
    "Hypertension in pregnancy",
    "HDP"
  ],
  "atlases": [
    "maternal"
  ],
  "summary_plain": "High blood pressure that is present before pregnancy or starts during it. NICE groups these disorders in three ways: high blood pressure that was there before pregnancy or appeared in the first 20 weeks (chronic hypertension), new high blood pressure that starts in the second half of pregnancy (called gestational hypertension), and new high blood pressure with signs that other organs are affected (pre-eclampsia). NICE puts the share of pregnant women affected at about 8% to 10%.",
  "summary_technical": "Umbrella for chronic hypertension, gestational hypertension and pre-eclampsia, as the NICE guideline NG133 groups them in its Context chapter. NG133 treats a systolic pressure of 140 mmHg or more, or a diastolic pressure of 90 mmHg or more, as hypertension, and gestational hypertension as high blood pressure that starts after 20 weeks of pregnancy with no significant protein in the urine. This atlas has records for chronic hypertension in pregnancy and for pre-eclampsia; gestational hypertension has no record of its own yet. Some guidance applies to the whole group (NG133 recommendations 1.9 and 1.10, and WHO 2020 for non-severe hypertension), which is why this umbrella exists. NG133 notes that its update did not review treatment for the three types of hypertension in pregnancy as one group. The maternal context is the default here; effects on the fetus or newborn sit in claims with their own contexts. WHO’s 2020 guideline says they are behind about 14% of maternal deaths around the world.",
  "editorial_state": "draft",
  "last_substantive_edit": "2026-10-11",
  "last_evidence_check": null,
  "next_review_due": null,
  "external_ids": [],
  "navigation": {
    "maternal": {
      "life-stage": [
        "pregnancy",
        "postpartum"
      ]
    }
  },
  "payload": {
    "taxonomy_codes": [],
    "recognition": null,
    "assessment": null,
    "burden_claims": []
  },
  "content_digest": "e98d0b788cf5f56d0d4f464681a98f628b2db6dcbeac3528e72ad35454501452",
  "review": {
    "content_digest": "e98d0b788cf5f56d0d4f464681a98f628b2db6dcbeac3528e72ad35454501452",
    "current": [],
    "conflicting": [],
    "stale": [],
    "inactive": []
  },
  "claims": [
    {
      "release_id": "15708f235d73cd42",
      "id": "maternal:claim-nice-ng133-1-10-2-later-cvd",
      "owner": "maternal",
      "subject_entity_id": "maternal:hypertensive-disorders-of-pregnancy",
      "category": "descriptive",
      "statement": "NICE (recommendation 1.10.2) tells clinicians to explain to women who had any type of hypertensive disorder during pregnancy that these disorders are linked with a raised chance of hypertension and cardiovascular disease as they get older. NICE’s Table 6 gives approximate sizes of the increase for each type of disorder.",
      "context": {
        "id": "maternal:ctx-nice-ng133-after-hdp-later-life",
        "label": "Women who have had a hypertensive disorder of pregnancy, later life (NICE NG133 recommendation 1.10.2)",
        "recipient": "maternal",
        "population": "Women who have had any hypertensive disorder of pregnancy (chronic hypertension, gestational hypertension or pre-eclampsia), compared by NICE with women who did not have one. The risks NICE reports are overall estimates drawn from several studies.",
        "care_setting": "Advice at transfer to community care after a hypertensive disorder of pregnancy.",
        "geography": "England. NICE's terms and conditions present the information on its websites as support for people in England who make decisions about funding care (clause 6) and say it is not written as a basis for decisions outside the United Kingdom (clause 8). The guideline page states no jurisdiction of its own.",
        "life_stage": "Postpartum and later life",
        "gestational_age_min_days": null,
        "gestational_age_max_days": null,
        "postnatal_age_min_days": null,
        "postnatal_age_max_days": null,
        "gestational_age_status": null,
        "postnatal_age_status": null,
        "followup_description": "NICE gives no single follow-up time: it says follow-up in the underlying studies ranged from 1 to 40 years postpartum.",
        "eligibility": {
          "inclusion": [
            "Women who have had a hypertensive disorder of pregnancy"
          ],
          "exclusion": [
            "Not stated in the recommendation"
          ]
        }
      },
      "evidence_stage": "guidance",
      "certainty": "not_assessed",
      "certainty_method": null,
      "limitations": "This is guidance that summarises other studies, not a new analysis. It covers any hypertensive disorder of pregnancy, so it must not be read as pre-eclampsia alone carrying the risk; Table 6 has separate columns for pre-eclampsia, gestational hypertension and chronic hypertension, and some cells say the risk may be increased or give no data. NICE says the figures in the table are overall estimates that condense results reported as risk, odds or hazard ratios, and that the comparison group is women who did not have a hypertensive disorder in pregnancy. Table 6 marks the later-hypertension row as not applicable for chronic hypertension. The table gives no absolute risks, since they depend on the follow-up time. The page does not state a jurisdiction; England is inferred from the issuer.",
      "editorial_state": "draft",
      "checked_at": null,
      "next_review_due": null,
      "valid_from": null,
      "valid_to": null,
      "citations": [
        {
          "evidence_role": "supports",
          "locator": "Recommendation 1.10.2, fragments 1 and 2",
          "applicability_note": "NICE guideline NG133; cited and linked only, with no NICE wording on public pages.",
          "snapshot": {
            "id": "maternal:nice-ng133-recs-2026-10-11",
            "retrieved_at": "2026-10-11T18:19:40Z",
            "content_hash": "0cd8548f5807f03a82b3101dc56ebadf674106da9d0aa7e57955d4a823556fca",
            "source_effective_date": "2023-04-17",
            "public_archive_url": null,
            "source_state": "current"
          },
          "source": {
            "id": "maternal:nice-ng133",
            "source_type": "guideline",
            "title": "Hypertension in pregnancy: diagnosis and management (NICE guideline NG133), Recommendations chapter",
            "canonical_url": "https://www.nice.org.uk/guidance/ng133/chapter/Recommendations",
            "identifier_namespace": "nice",
            "identifier_value": "NG133",
            "publication_date": "2019-06-25",
            "publisher": "National Institute for Health and Care Excellence (NICE)",
            "edition": "The version shown on 2026-10-11, with a page header that gives 17 April 2023 as the last update. The same bytes came back on a second fetch minutes later.",
            "reuse_basis": "The page bytes are not committed. Public text is cite_only (Ben's decision of 2026-10-13 (medical-atlas-core issue 2)): public pages state the facts in the atlas's own words, with a citation and a link, and use no NICE wording. NICE reuse terms, read on 2026-10-11: the NICE UK Open Content Licence covers use in a UK setting only, international use outside personal research and study needs a licence and a fee, and the NICE terms and conditions make content available for artificial intelligence purposes only through an approval process, a licence and a fee for international use. This pipeline uses AI agents to read the page, so Ben decided on 2026-10-13 that public pages cite and link NICE and use none of its wording.",
            "public_text": "cite_only"
          }
        },
        {
          "evidence_role": "context",
          "locator": "Table 6, column heading",
          "applicability_note": "Chronic hypertension has its own column.",
          "snapshot": {
            "id": "maternal:nice-ng133-recs-2026-10-11",
            "retrieved_at": "2026-10-11T18:19:40Z",
            "content_hash": "0cd8548f5807f03a82b3101dc56ebadf674106da9d0aa7e57955d4a823556fca",
            "source_effective_date": "2023-04-17",
            "public_archive_url": null,
            "source_state": "current"
          },
          "source": {
            "id": "maternal:nice-ng133",
            "source_type": "guideline",
            "title": "Hypertension in pregnancy: diagnosis and management (NICE guideline NG133), Recommendations chapter",
            "canonical_url": "https://www.nice.org.uk/guidance/ng133/chapter/Recommendations",
            "identifier_namespace": "nice",
            "identifier_value": "NG133",
            "publication_date": "2019-06-25",
            "publisher": "National Institute for Health and Care Excellence (NICE)",
            "edition": "The version shown on 2026-10-11, with a page header that gives 17 April 2023 as the last update. The same bytes came back on a second fetch minutes later.",
            "reuse_basis": "The page bytes are not committed. Public text is cite_only (Ben's decision of 2026-10-13 (medical-atlas-core issue 2)): public pages state the facts in the atlas's own words, with a citation and a link, and use no NICE wording. NICE reuse terms, read on 2026-10-11: the NICE UK Open Content Licence covers use in a UK setting only, international use outside personal research and study needs a licence and a fee, and the NICE terms and conditions make content available for artificial intelligence purposes only through an approval process, a licence and a fee for international use. This pipeline uses AI agents to read the page, so Ben decided on 2026-10-13 that public pages cite and link NICE and use none of its wording.",
            "public_text": "cite_only"
          }
        },
        {
          "evidence_role": "context",
          "locator": "Table 6, notes",
          "applicability_note": "How to read the table.",
          "snapshot": {
            "id": "maternal:nice-ng133-recs-2026-10-11",
            "retrieved_at": "2026-10-11T18:19:40Z",
            "content_hash": "0cd8548f5807f03a82b3101dc56ebadf674106da9d0aa7e57955d4a823556fca",
            "source_effective_date": "2023-04-17",
            "public_archive_url": null,
            "source_state": "current"
          },
          "source": {
            "id": "maternal:nice-ng133",
            "source_type": "guideline",
            "title": "Hypertension in pregnancy: diagnosis and management (NICE guideline NG133), Recommendations chapter",
            "canonical_url": "https://www.nice.org.uk/guidance/ng133/chapter/Recommendations",
            "identifier_namespace": "nice",
            "identifier_value": "NG133",
            "publication_date": "2019-06-25",
            "publisher": "National Institute for Health and Care Excellence (NICE)",
            "edition": "The version shown on 2026-10-11, with a page header that gives 17 April 2023 as the last update. The same bytes came back on a second fetch minutes later.",
            "reuse_basis": "The page bytes are not committed. Public text is cite_only (Ben's decision of 2026-10-13 (medical-atlas-core issue 2)): public pages state the facts in the atlas's own words, with a citation and a link, and use no NICE wording. NICE reuse terms, read on 2026-10-11: the NICE UK Open Content Licence covers use in a UK setting only, international use outside personal research and study needs a licence and a fee, and the NICE terms and conditions make content available for artificial intelligence purposes only through an approval process, a licence and a fee for international use. This pipeline uses AI agents to read the page, so Ben decided on 2026-10-13 that public pages cite and link NICE and use none of its wording.",
            "public_text": "cite_only"
          }
        },
        {
          "evidence_role": "context",
          "locator": "Table 6, row Stroke, gestational hypertension column",
          "applicability_note": "Not every cell says the risk is increased.",
          "snapshot": {
            "id": "maternal:nice-ng133-recs-2026-10-11",
            "retrieved_at": "2026-10-11T18:19:40Z",
            "content_hash": "0cd8548f5807f03a82b3101dc56ebadf674106da9d0aa7e57955d4a823556fca",
            "source_effective_date": "2023-04-17",
            "public_archive_url": null,
            "source_state": "current"
          },
          "source": {
            "id": "maternal:nice-ng133",
            "source_type": "guideline",
            "title": "Hypertension in pregnancy: diagnosis and management (NICE guideline NG133), Recommendations chapter",
            "canonical_url": "https://www.nice.org.uk/guidance/ng133/chapter/Recommendations",
            "identifier_namespace": "nice",
            "identifier_value": "NG133",
            "publication_date": "2019-06-25",
            "publisher": "National Institute for Health and Care Excellence (NICE)",
            "edition": "The version shown on 2026-10-11, with a page header that gives 17 April 2023 as the last update. The same bytes came back on a second fetch minutes later.",
            "reuse_basis": "The page bytes are not committed. Public text is cite_only (Ben's decision of 2026-10-13 (medical-atlas-core issue 2)): public pages state the facts in the atlas's own words, with a citation and a link, and use no NICE wording. NICE reuse terms, read on 2026-10-11: the NICE UK Open Content Licence covers use in a UK setting only, international use outside personal research and study needs a licence and a fee, and the NICE terms and conditions make content available for artificial intelligence purposes only through an approval process, a licence and a fee for international use. This pipeline uses AI agents to read the page, so Ben decided on 2026-10-13 that public pages cite and link NICE and use none of its wording.",
            "public_text": "cite_only"
          }
        },
        {
          "evidence_role": "context",
          "locator": "Table 6, row Hypertension, gestational hypertension and chronic hypertension columns",
          "applicability_note": "The chronic hypertension cell is marked not applicable.",
          "snapshot": {
            "id": "maternal:nice-ng133-recs-2026-10-11",
            "retrieved_at": "2026-10-11T18:19:40Z",
            "content_hash": "0cd8548f5807f03a82b3101dc56ebadf674106da9d0aa7e57955d4a823556fca",
            "source_effective_date": "2023-04-17",
            "public_archive_url": null,
            "source_state": "current"
          },
          "source": {
            "id": "maternal:nice-ng133",
            "source_type": "guideline",
            "title": "Hypertension in pregnancy: diagnosis and management (NICE guideline NG133), Recommendations chapter",
            "canonical_url": "https://www.nice.org.uk/guidance/ng133/chapter/Recommendations",
            "identifier_namespace": "nice",
            "identifier_value": "NG133",
            "publication_date": "2019-06-25",
            "publisher": "National Institute for Health and Care Excellence (NICE)",
            "edition": "The version shown on 2026-10-11, with a page header that gives 17 April 2023 as the last update. The same bytes came back on a second fetch minutes later.",
            "reuse_basis": "The page bytes are not committed. Public text is cite_only (Ben's decision of 2026-10-13 (medical-atlas-core issue 2)): public pages state the facts in the atlas's own words, with a citation and a link, and use no NICE wording. NICE reuse terms, read on 2026-10-11: the NICE UK Open Content Licence covers use in a UK setting only, international use outside personal research and study needs a licence and a fee, and the NICE terms and conditions make content available for artificial intelligence purposes only through an approval process, a licence and a fee for international use. This pipeline uses AI agents to read the page, so Ben decided on 2026-10-13 that public pages cite and link NICE and use none of its wording.",
            "public_text": "cite_only"
          }
        }
      ],
      "review": {
        "content_digest": "0bbb432843b9370cabbb34e5f5a83f10485ed84a468dcc9c0709bc23d6a01756",
        "current": [],
        "conflicting": [],
        "stale": [],
        "inactive": []
      },
      "api_path": "api/v1/claims/maternal--claim-nice-ng133-1-10-2-later-cvd.json"
    }
  ],
  "decisions": [],
  "relationships": {
    "outgoing": [
      {
        "predicate": "increases_risk_of",
        "label": "Hypertensive disorders of pregnancy are associated with a higher later risk of hypertension and cardiovascular disease (NICE NG133 1.10.2)",
        "clinical_claim_not_fact": true,
        "other_entity_id": "core:hypertension",
        "other_entity_in_atlas": true,
        "claim_id": "maternal:claim-nice-ng133-1-10-2-later-cvd"
      }
    ],
    "incoming": [
      {
        "predicate": "subtype_of",
        "label": "Has subtype",
        "clinical_claim_not_fact": false,
        "other_entity_id": "maternal:chronic-hypertension-in-pregnancy",
        "other_entity_in_atlas": true,
        "claim_id": null
      },
      {
        "predicate": "subtype_of",
        "label": "Has subtype",
        "clinical_claim_not_fact": false,
        "other_entity_id": "maternal:preeclampsia",
        "other_entity_in_atlas": true,
        "claim_id": null
      },
      {
        "predicate": "recommended_for",
        "label": "Recommended for this",
        "clinical_claim_not_fact": true,
        "other_entity_id": "maternal:antihypertensive-treatment-non-severe-hypertension-pregnancy",
        "other_entity_in_atlas": true,
        "claim_id": "maternal:claim-nice-ng133-1-3-9-target"
      },
      {
        "predicate": "recommended_for",
        "label": "Recommended for this",
        "clinical_claim_not_fact": true,
        "other_entity_id": "maternal:antihypertensive-treatment-non-severe-hypertension-pregnancy",
        "other_entity_in_atlas": true,
        "claim_id": "maternal:claim-who-2020-nonsevere-htn"
      }
    ]
  },
  "page_path": "conditions/hypertensive-disorders-of-pregnancy/",
  "context_path": "api/v1/context/maternal--hypertensive-disorders-of-pregnancy.md"
}
